Formamidine acetate, eo hape e tsejoang e le N, N-dimethylformamidine acetate kapa CAS No. 3473-63-0, ke motsoako oa bohlokoa o phethang karolo ea bohlokoa ho nts'etsopele ea lithethefatsi.K'hemik'hale ena e hohetse tlhokomelo e kholo indastering ea meriana ka lebaka la thepa ea eona e mengata le mekhoa e ka 'nang ea e-ba teng ea phekolo.
E 'ngoe ea thepa ea bohlokoa ea formamidine acetate ke bokhoni ba eona ba ho sebetsa e le setsi se matla le nucleophile.Sena se bolela hore e ka kenya letsoho ka matla liphetohong tsa lik'hemik'hale, e leng se etsang hore e be karolo ea bohlokoa tlhahisong ea meriana e mengata.Reactivity ea eona e ikhethang e e lumella hore e sebelisoe mefuteng e fapaneng ea litlhare, ho kenyelletsa le nts'etsopele ea li-antiviral, antibacterial le antifungal drugs.
Formamidine acetatee bontšitse bokhoni bo boholo joalo ka moemeli oa antiviral.Ts'ebetso ea eona khahlano le livaerase tsa DNA le RNA, ho kenyelletsa kokoana ea herpes simplex (HSV) le kokoana-hloko ea immunodeficiency virus (HIV), e ithutoe haholo.Bafuputsi ba fumane hore motsoako o thibela ho ikatisa ha kokoana-hloko ka ho kena-kenana le li-enzyme tsa kokoana-hloko, kahoo li thibela bokhoni ba tsona ba ho ikatisa ka har'a lisele tse amohelang.Ka lebaka la matšoenyeho a ntseng a hola mabapi le ho phatloha ha vaerase le tlhoko ea liphekolo tse sebetsang tsa antiviral, formamidine acetate e lebelletsoe ho ba mokhethoa ea ka bang teng bakeng sa nts'etsopele ea litlhare tsa antiviral tse ncha.
Ho phaella moo, formamidine acetate e bontšitse thepa e matla ea antimicrobial.E 'nile ea ithutoa ka katleho ea eona khahlanong le mefuta e fapaneng ea libaktheria, ka bobeli Gram-positive le Gram-negative.Liphuputso li bontšitse hore motsoako ona o ka senya lera la lisele tsa baktheria, oa thibela kholo ea baktheria le ho ikatisa.E boetse e fumanwe hore e matlafatsa tshebetso ya dithibela-mafu tse seng di ntse di le teng, ho e etsa tlatsetso e ka bang teng twantshong ya dibaktheria tse hanyetsanang le dithibela-mafu.
Kopo e 'ngoe ea bohlokoa eaformamidine acetatee itšetlehile ka matla a eona a antifungal.Tšoaetso ea fungal e baka tšokelo e kholo ho bophelo bo botle ba batho, haholo-holo ho batho ba sa tsebeng ho itšireletsa mafung.Motsoako o bontšitse liphello tse tšepisang ho thibela ho hōla ha li-fungus tsa pathogenic ka ho senya lisele tsa bona tsa lisele le ho kena-kenana le mekhoa ea bona ea metabolism.Ha fungal e hanyetsa lithethefatsi tsa antifungal e ntse e ata haholoanyane, formamidine acetate e fana ka mokhoa o mocha oa nts'etsopele ea lithethefatsi tse thibelang likokoana-hloko.
Formamidine acetate e boetse e sebelisoa e le ntho e ka sehloohong ea ho kopanya metsoako e mengata ea meriana.Sebopeho sa eona se ikhethang sa lik'hemik'hale le reactivity e etsa hore e be thepa e tala e loketseng bakeng sa tlhahiso ea meriana e sa tšoaneng.Ho feta moo, motsoako oa eona o sebetsang hantle le ho fumaneha habonolo ho kenya letsoho ho tumang ha eona ntlafatsong ea lithethefatsi.
Ha re phethela,formamidine acetateka nomoro ea CAS 3473-63-0 e phetha karolo ea bohlokoa ntlafatsong ea lithethefatsi.Bokhoni ba eona ba ho sebetsa e le setsi se matla le nucleophile, hammoho le thepa ea eona e matla ea antiviral, antibacterial le antifungal, e etsa hore e be mokhethoa ea khahlehang bakeng sa nts'etsopele ea li-agent tse ncha tsa phekolo.Phuputso e tsoelang pele ea formamidine acetate lipatlisisong tsa meriana e tlisa tšepo e kholo bakeng sa ho sibolloa ha lithethefatsi nakong e tlang le kalafo ea mafu a fapaneng a tšoaetsanoang.
Nako ea poso: Jun-20-2023