DMTCl44′Dimethoxytrityl CAS 40615-36-9
Ho hlahisa DMTCl4 4 'Dimethoxytrityl - tharollo ea ho qetela bakeng sa ts'ireletso ea sehlopha e sebetsang, ho felisa le ho sireletsa hydroxyl ea nucleosides le nucleotide.Ka bohloeki ba eona bo ikhethang ≥ 98%, kristale ena e pinki e mosehla e nepahetse bakeng sa merero eohle ea hau ea lipatlisiso le nts'etsopele.
Lintho tsa Lik'hemik'hale
Bakeng sa polokelo, DMTCl4'Dimethoxytrityl e hloka mocheso oa 2 ho isa ho 8°C bakeng sa botsitso bo nepahetseng.Leha ho le joalo, ka lebaka la bohloeki ba eona bo phahameng, e ka bolokoa nako e telele ntle le ho senyeha kapa ho lahleheloa ke boleng.
Lisebelisoa
DMTCl44'Dimethoxytrityl ke sehlopha se sireletsang haholo se etselitsoeng ho sireletsa lihlopha tse sebetsang ka har'a metsoako ea lintho tse phelang tse kang amine, carboxyls le alcohols.E sebelisoa haholo ho organic synthesis le chemistry ea peptide bakeng sa ts'ireletso ea li-amine tsa mantlha le tsa bobeli ho tsoa ho li-reagents tse fapaneng.
Ho phaella ho bokhoni ba eona ba ho sireletsa sehlopha, DMTCl44'Dimethoxytrityl e boetse e le mokelikeli o ka sebelisoang ho tlosa lihlopha tsa hydroxyl ho li-nucleotide kapa nucleosides.Sena se bohlokoa haholo ha ho etsoa li-nucleotide analogues, moo boteng ba lihlopha tsa hydroxyl bo ka lebisang liketsong tse sa batleheng tsa lehlakore.
Ho feta moo, DMTCl44'Dimethoxytrityl e sebetsa e le ntho e ntle haholo e sireletsang hydroxyl bakeng sa li-nucleosides le nucleotide.E sireletsa lihlopha tsa hydroxyl maemong a 3' kapa 5' a ribonucleosides kapa deoxyribonucleosides ho tsoa ho maikutlo a sa batleheng.
Ka bokhutšoanyane, haeba u batla li sireletsang sehlopha tse sebetsang hantle haholo, li-eliminator le li sireletsang hydroxyl bakeng sa li-nucleoside le li-nucleotide, ha ho na tharollo e molemo ho feta DMTCl4 4' Dimethoxytrityl.Ka bohloeki ba eona bo ikhethang, ho boloka habonolo le mefuta e mengata ea lisebelisoa, DMTCl4 4' Dimethoxytrityl e loketse litlhoko tsohle tsa hau tsa organic synthesis le chemistry ea peptide.